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スループットを求めた． 理論計算とシミュレーション評価の結果を比較すると，
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For people with symptomatic illness demanding therapy, ibrutinib is often recommended determined by four period III randomized medical trials comparing ibrutinib with chlorambucil monotherapy106 and also other frequently utilised CIT combinations, specifically FCR, bendamustine additionally rituximab and chlorambucil moreover obinutuzumab (ClbO).107–109 Ibrutinib was outstanding to chlorambucil and all CIT combinations when it comes to reaction amount and development-cost-free survival, and in some cases conferred a longer overall survival compared to that furnished by chlorambucil monotherapy and FCR.
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mutations, dropped their detrimental result in sufferers taken care of with VO. The only factor that remained predictive of the shorter development-cost-free survival On this cohort of individuals was TP53
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結び目の数学 絡み目を平面に射影し，線が交差しているところに上下 の情報をつけたものを絡み目の 図式 という．.
Latest molecular research have delivered many insights in the processes that govern the development and progression of CLL, such as several novel mutated genes clustered in several functional pathways. The CLL epigenome is reprogrammed in the modulation of regulatory regions that look de novo
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